Delayed Maturation of C D 4 - C D 8 - Fc ~ / RII / III + T and Natural Killer Cell Precursors in FceRI ~ / Transgenic Mice
نویسندگان
چکیده
From the *Laboratory of MolecularAllergy & Immunology, National h;stitute of Allergy and Infectious Diseases, National h;stitutes of Health, Rockville, Maryland 20852; ~;Division of Hematologic Products, Center for Biologics Evaluation and Research, Food and Dn,g Administration, Bethesda, Maryland 20892; and the ~Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892
منابع مشابه
Delayed maturation of CD4- CD8- Fc gamma RII/III+ T and natural killer cell precursors in Fc epsilon RI gamma transgenic mice
Fc epsilon RI gamma (gamma) is a member of a group of related proteins (the zeta-family dimers) that function as signal-transducing components of both Fc receptors and the T cell antigen receptor (TCR). Analysis of gamma expression during fetal thymus ontogeny revealed that it is expressed in early thymocytes, before the initiation of clonotypic TCR-alpha and TCR-beta gene rearrangement but is ...
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